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Case Studies & Whitepapers2025-04-23

Challenges and Advances in CMC Process Development of BsADCs Download

Antibody drug conjugates (ADCs) have seen significant breakthroughs and reached numerous milestones since 2000 when the first ADC was approved by the FDA and have shown great promise for the treatment of cancer. First generation ADCs were designed to use the affinity of an antibody towards a specific cellular target to bring the cytotoxic payload to the tumor, for example. However, some level of off-target toxicity was often seen with many ADCs because other cellular interactions could occur pri
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Flow Chemistry

Case Studies & Whitepapers2025-06-04

Flow Chemistry: A New Technology to Enhance the Traditional Batch Process in the Delivery Requirement

Continuous reaction can effectively solve the problem of "amplification effect" in batch processes from research and development to pilot testing, and then again to commercial production. Porton’s continuous reaction capabilities include low-temperature lithiation reaction, ozone oxidation reaction, nitrification reaction, high-temperature reaction, and organic azide reaction, etc., which can achieve process development and technology transfer from research and development to production application.

Case Studies & Whitepapers2025-04-27

Comprehensive Analytical R&D and QC Expertise in Pharmaceutical Development

This white paper details our extensive capabilities in Analytical Research and Development (R&D) and Quality Control (QC) for pharmaceutical drug development. It highlights our expertise in method development, structure elucidation, and method troubling. Our goal is to ensure the highest standards of quality and efficiency in drug development and manufacturing.
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